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Fakultät Bio- und Chemieingenieurwesen
© LS APT​/​TU Dortmund
Alumni

M.Sc. Justin Simons

Profile picture: Justin Simons

Curriculum Vitae

Born

December 23rd, 1997 in Bonn (Germany)
2008-2016
Vinzenz-Pallotti-Kolleg, Rheinbach (Germany)
2016-2020
B.Sc. Chemical Engineering Studies, TU Dortmund University

Bachelor thesis: Development of a Method for determining the Primary Nucleation Threshold in a Continous Oscillatory Baffled Crystallize
2020-2021
M.Sc. Chemical Engineering Studies, TU Dortmund University

Master thesis: Development of an inter gassing crystallization and solid-liquid separation for an integrated catalyst recycling process
2022-2023
PhD at the Laboratory of Plant and Process Design, TU Dortmund University

Field of Research: Continuous crystallization, Continuous solid-liquid separation

Field of Research

For the paradigm shift from batch to continuous operation in pharmaceutical industry, innovative process solutions are required to extend unit operations that have historically been batch operations, such as crystallization. Different concepts for continuous crystallization are present to improve the product qualities such as crystal size, shape, and purity. However, crystallization needs additional downstream processes as filtration, washing and drying to obtain the final product.

These continuous isolation techniques are relatively rare in the pharmaceutical industry and specialty chemical industry, because of relatively low production capacities. The lack of commercial laboratory and manufacturing continuous filtration units leads to a significant gap in the development of full continuous manufacturing processes. Thus, a continuous small-scale solid/liquid filtration device will be developed and characterized. Subsequently, the device will be connected to different continuous crystallizers to enable a full continuous process.
Funding: This research work is funded by the state of North-Rhine Westphalia (NRW) and the European Regional Development Fund (EFRE), Project “NRW Patent Validation Program” (Grant EFRE-0400357)

Publications

Paper

  • Astrid Ina Seifert, Justin Simons, Jan Gutsch, Kerstin Wohlgemuth
    Inert gassing crystallization for improved product separation of oleo-chemicals towards an efficient circular economy
    Organic Process Research & Development (12/2022), https://doi.org/10.1021/acs.oprd.2c00312
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