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Fakultät Bio- und Chemieingenieurwesen
© LS APT​/​TU Dortmund

Contact

E-Mail:
sophia.volperttu-dortmundde

Phone:
(+49)231 755-6772

Consultation hours:
via Email

Adress

Laboratory of Plant and Process Design
Emil-Figge-Str. 70
Geschossbau 2
44227 Dortmund
Deutschland

Room G2-R3.16

Curriculum Vitae

Born June 10th, 1997 in Olpe (Germany)
2007 - 2015 St. Franziskus-Gymnasium, Olpe (Germany)
2015 - 2019 B.Sc. Biochemical Engineering Studies, TU Dortmund University
Bachelor thesis: Messung und Modellierung der Löslichkeit von Dipeptiden in wässrigen und nicht-wässrigen Lösungen
2019 - 2021 M.Sc. Biochemical Engineering Studies, TU Dortmund University
Master Thesis: Simulation of Hydrodynamics within Centrifugal Partition Chromatography using Computational Fluid Dynamics
Since 2022 PhD at the Laboratory of Plant and Process Design, TU Dortmund University
Field of Research: Continuous Centrifugal Extraction

Field of Research

The application of unstable phase systems (like aqueous two-phase systems) in conventional extraction processes is challenging due to poor phase separation and resulting long phase settling times. The development of the continuous centrifugal extraction (CCE), which is based on the technology of centrifugal partition chromatography (CPC), provides a benefit, as the use of centrifugal forces enhances phase separation and additionally supports phase mixing. Both liquid phases are pumped continuously in counter-current direction through a chamber cascade inside a rotor. A third stream containing the sample to be separated can continuously be fed somewhere in the middle of the chamber cascade.This transfer from a batch process (CPC) to a continuous one (CCE) leads to a significant increase in overall productivity.

 

Publications

Paper

  • Buthmann, Hohlmann, Volpert, Neuwald, Hamza, Schembecker
    Counteracting Bleeding in Centrifugal Partition Chromatography: Redosing of the Stationary Phase
    Separations (2024), 11(4), 98 doi.org/10.3390/separations11040098
     
  • Buthmann, Volpert, Koop, Schembecker
    Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography
    Separations (2024) doi.org/10.3390/separations11010016

Oral presentations

  • Volpert, Nordhausen, Alfsmann, Schembecker
    Continuous Centrifugal Extraction: Optimization of Hydrodynamics based on Computational Fluid Dynamics and Additive Manufacturing
    Himmelfahrtstagung on Bioprocess Engineering (2023), Weimar
     
  • Volpert, Nordhausen, Alfsmann, Schembecker
    Continuous Centrifugal Extraction: Optimization of Hydrodynamics and Construction of a Modular Rotor
    ECCE/ECAB (2023), Berlin

Poster presentations

  • Volpert, Nordhausen, Alfsmann, Schembecker
    Continuous Centrifugal Extraction: Hydrodynamics in Separation Chambers with simultaneous Mixing and Settling
    Fachausschusstagung Extraktion (2023), Frankfurt
     
  • Volpert, Buthmann, Koop, Schembecker
    Towards Analysis of Hydrodynamics within Continuous Centrifugal Extraction using Computational Fluid Dynamics
    Himmelfahrtstagung on Bioprocess Engineering (2022), Mainz
     
  • Volpert, Koop, Schembecker
    Continuous Centrifugal Extraction: Technical Challenges and their Solutions
    (Bio)Process Engineering/ProcessNet (2022), Aachen
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