Dr.-Ing. Niklas Wolters

In food industry a huge amount of biogenic waste streams is produced as side products, which cannot be applied for further processing. As a result these biogenic waste streams are preferable applied as feed stock for animals or thermal energy production. To avoid this loss a promising approach is the utilization of waste streams as substrates for biotechnical processes. Especially some edible basidiomycota are industrially bred and applied in asia as medicinal fungi.

Objective of the project is the application of different biogenic waste streams for submerged cultivation of the fungus Hericium erinaceus. The focus of this study is to optimize the growth of the fungus as well as the stimulation of production of erinacines. These molecules are said to cause the medicative effect of the fungus. Beside the development of an optimal set up for fermentation, established methods of downstream processing are performed and modified to purify the molecules of interest

Dissertation

• N. Wolters
  On the Biotechnological Production of Erinacine C based on Biogenic Byproducts
  TU Dortmund, 2018, Verlag Dr. Hut, München ISBN 978-3-8439-3629-3

Paper

• N. Wolters, C. Schabronath, G. Schembecker and J. Merz
  Efficient conversion of pretreated brewer’s spent grain and wheat bran by submerged cultivation of Hericium erinaceus
  Bioresource Technology, 222 (2016), 123-129, doi.org/10.1016/j.biortech.2016.09.121
   
• N. Wolters, G. Schembecker, J. Merz
  Erinacine C: A Novel Approach to Produce the Secondary Metabolite by Submerged Cultivation of Hericium erinaceus
  Fungal Biology, 119 (2015) 1334–1344, doi.org/10.1016/j.funbio.2015.10.005

Oral presentations

• J. Krause, N. Wolters, D. Janz, G. Schembecker and J. Merz
  Centrifugal Partition Chromatography for the Separation of Complex Mixtures
  12th International PhD Seminar on Chromatographic Separation Science, Schleiden, Germany (2016)
   
• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  A Novel Approach to Utilize Filamentous Fungi for Production of Functional Food Ingredients
  CLIB International Conference 2016, Düsseldorf, Germany (2016)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Biogenic Waste Streams to High Valuable Food Products
  10th European Congress of Chemical Engineering, Nice, France (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Biogenic Waste Streams to High Valuable Food Products
  Sixth Annual Retreat of the CLIB-Graduate Cluster, Wermelskirchen, Germany (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Umsetzung biogener Restströme zu hochwertigen Lebensmittelzusätzen
  ProcessNet-Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany (2014)

Poster presentations

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  A Novel Approach to Utilize Fungi For Production of Secondary Metabolites
  3rd European Congress of Applied Biotechnology, Nice, France (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Production of High Value Food Products by Fermentation of Biogenic Waste Streams
  Scale-up and scale-down of bioprocesses, Hamburg, Germany (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Production of High Value Food Products by Fermentation of Biogenic Waste Streams
  1st Industrial Bioprocess-Development Academy, Ludwigshafen, Germany (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Production of High Quality Food Products from Biogenic Waste Streams
  Sixth Annual Retreat of the CLIB-Graduate Cluster, Wermelskirchen, Germany (2015)

• Niklas Wolters, Gerhard Schembecker, Juliane Merz
  Production of High Quality Food Products from Biogenic Waste Streams
  Fifth Annual Retreat of the CLIB-Graduate Cluster, Lünen, Germany (2014)