Dr.-Ing. Mareike Schreiber-Choo
Curriculum Vitae
| Born | April 30th, 1994 in Kassel (Germany) |
| 2010–2013 | Georg-Christoph-Lichtenberg-Schule, Kassel (Germany) |
| 2013–2017 | B.Sc. Chemical Engineering Studies, TU Dortmund University Bachelor thesis: Experimental and Theoretical Investigation of the Predictability of Solvent Flux Through Organic Solvent Nanofiltration Membranes |
| 2017–2018 | M.Sc. Chemical Engineering Studies, TU Dortmund University Master thesis: Towards Characterization of a Continuous Oscillatory Baffled Crystallizer Using Small Volume Flow Rates |
| 2019-2022 | PhD at the Laboratory of Plant and Process Design, TU Dortmund University |
Field of Research
For biotechnological products, a great amount of costs results from purification steps during downstream processing. In the present work, the main objective is to develop a platform that autonomously synthesizes and executes a downstream process based on heuristics, screening tests and statistical experiments. Thereby, the focus lies on steroid purification from a fermentation broth.
For this purpose, a robotic platform (Zinsser Analytic) is utilized which executes several unit operations in a miniaturized dimension and in an automated manner. Thus, material consumption, manual effort and variances of experimental results are minimized. Key performance indicators are applied to identify an economically optimized process with regard to costs, yield and purity.
As a result, suitable purification steps as well as optimal process conditions can be determined with the aid of the robotic platform.
Publications
Dissertation
- M. Schreiber-Choo
Perspectives for Autonomous Downstream Process Synthesis of Biochemical Products on a Robotic Platform
TU Dortmund, 2023, Verlag Dr. Hut, München, ISBN 978-3-8439-5409-9
Paper
- M. Schreiber, G. Schembecker
Development of an Automated Adsorbent Selection Strategy for Liquid–Phase Adsorption
Chemical Engineering and Technology 45 (2022), No. 6, 1124-1132, doi.org/10.1002/ceat.202200152
- M. Schreiber, M. Brunert, G. Schembecker
Extraction on a Robotic Platform - Autonomous Solvent Selection under Economic Evaluation Criteria
Chemical Engineering and Technology 44 (2021), No. 9, 1578-1584, doi.org/10.1002/ceat.202100171
Poster presentation
- M. Schreiber, G. Schembecker
Towards autonomous selection of adsorbents on a robotic platform utilizing economic evaluation indicators
13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology, Virtual Meeting (2021)
- M. Schreiber, L. Orth, G. Schembecker
Towards Industry 4.0 - Autonomous Design of an Adsorption - Desorption Process on a Robotic Platform
Jahrestreffen der ProcessNet-Fachgruppe Prozess-, Apparate- und Anlagentechnik, Virtual Meeting (2021)
- M. Schreiber, G. Schembecker
Approach for an Automated Synthesis of Downstream Processes Using a Robotic Platform
Himmelfahrtstagung 2019, Hamburg, GER (2019)
Oral presentation
- M. Schreiber, G. Schembecker
Towards Automated Downstream Process Design - Development of a Tool for Autonomous Adsorbent Selection
Jahrestreffen der ProcessNet Fachgruppe Adsorption, Frankfurt, GER (2021)
- M. Schreiber, M. Brunert, G. Schembecker
Advances in Industry 4.0 – Development of a Smart Robotic Platform for Autonomous Synthesis of Downstream Processes
Pre-recorded +, Virtual AIChE Annual Meeting, 2020
- M. Schreiber, G. Schembecker
Liquid-Liquid Extraction on a Robotic Platform – A Step towards Automated Downstream Process Design
Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Adsorption und Extraktion
Berchtesgaden, GER (2020)