Dr.-Ing. Juliane Merz

Innovative Downstream Processes

Dissertation

• J. Merz
  A contribution to design foam fractionation processes
  TU Dortmund, 2012, Verlag Dr. Hut, München, ISBN 978-3-8439-0685-2

Paper

• J. Koop, J. Merz, G. Schembecker
  Hydrophobicity, amphilicity, and flexibility: Relation between molecular protein properties and the macroscopic effects of surface activity
  Journal of Biotechnology 334 (2021), 11-25 (doi.org/10.1016/j.jbiotec.2021.05.002)
   
• J. Koop, J. Merz, C. Pietzsch, G. Schembecker
  Contribution of Secondary Structure Changes to the Surface Activity of Proteins
  Journal of Biotechnology 323 (2020) 208-220 (doi.org/10.1016/j.jbiotec.2020.07.015)
   
• Fromme, A., Funke, F., Merz, J., Schembecker, G.
  Correlating physical properties of aqueous-organic solvent systems and stationary phase retention in a centrifugal partition chromatograph in descending mode
  Journal of Chromatography A (2020) - doi.org/10.1016/j.chroma.2019.460742
   
• J. Koop, J. Merz, R. Wilmshöfer, R. Winter, G. Schembecker
  Influence of thermally induced structure changes in diluted β-lactoglobulin solutions on their surface activity and behavior in foam fractionation
  Journal of Biotechnology 319 (2020) 61-68 (doi.org/10.1016/j.jbiotec.2020.05.011)
   
• Wetzel, D., Barbian, A., Jenzelewski, V., ...Merz, J., Piontek, M., Schembecker, G.
  Bioprocess optimization for purification of chimeric VLP displaying BVDV E2 antigens produced in yeast Hansenula polymorpha
  Journal of Biotechnology, 2019, 306, pp. 203-212, doi.org/10.1016/j.jbiotec.2019.10.008
   
• Kaplanow, I., Goerzgen, F., Merz, J., Schembecker, G.
  Mass Transfer of Proteins in Aqueous Two-Phase Systems
  Scientific Reports 9(1) ( 2019) 3692, Article

• Kaplanow, I., Stecker, J., Schembecker, G., Merz, J.
  Multistage Processing of Tunable Aqueous Polymer Phase Impregnated Resins (TAPPIR®)
  Chemical Engineering and Technology41(7)(2018), pp. 1324-1330 (doi.org/10.1002/ceat.201800079)
   
• I.Lukin, J.Merz, G.Schembecker.
  Techniques for the recovery of volatile aroma compounds from biochemical broth: A review
  Flavour and Fragrance Journal 33. 3 ( 2018), pp. 203-216 (doi.org/10.1002/ffj.3447)
   
• D.Wetzel, T.Rolf, M.Suckow, , (...), J.Merz, Piontek, M.
  Establishment of a yeast-based VLP platform for antigen presentation
  2018 Microbial Cell Factories17. 1 (2018),17 (Article)
   
• I. Kaplanow, M. Schmalenberg, I. Borgmann, G. Schembecker, J. Merz
  Tunable Aqueous Polymer Phase Impregnated Resins (TAPPIR®): Investigation of the impregnation stability
  Separation and Purification Technology, 190 (2017) 1-8 (doi.org/10.1016/j.seppur.2017.08.022)
   
• J. Krause and J. Merz
  Hydrodynamic influences on the reaction performance of a crude yeast lysate in the CPC reactor
  Biochem. Eng. J. (2017), (doi.org/10.1016/j.bej.2017.05.025)
   
• J. Krause and J. Merz
  Comparison of enzymatic hydrolysis in a centrifugal partition chromatograph and stirred tank reactor
  Journal of Chromatography A (2017), 1504, 64-70, (doi.org/10.1016/j.chroma.2017.05.006)
   
• C. Schwienheer, J. Krause, G. Schembecker, J. Merz
  Modelling centrifugal partition chromatography separation behavior to characterize influencing hydrodynamic effects on separation efficiency
  Journal of Chromatography A,1492 ( 2017)  27–40 (doi.org/10.1016/j.chroma.2017.02.055)
   
• J. Krause, R. Krutz, G. Schembecker and J.Merz
  Whole cell immobilization and catalysis in a Centrifugal Partition Chromatograph
  Biochemical Engineering Journal, 117 Part A (2017) 188-197, (doi.org/10.1016/j.bej.2016.10.015)
   
• N. Wolters, C. Schabronath, G. Schembecker and J. Merz
  Efficient conversion of pretreated brewer’s spent grain and wheat bran by submerged cultivation of Hericium erinaceus
  Bioresource Technology, 222 (2016), 123-129, (doi.org/10.1016/j.biortech.2016.09.121)

• F. Thygs, J. Merz, and G. Schembecker
  Automation of Solubility Measurements on a Robotic Platform
  Journal of Chemical and Engineering Technology 39 (2016) 1049-1057, (doi.org/10.1002/ceat.201500572)

• B. Dreisewerd, J. Merz, and G. Schembecker
  Modeling the Quasi-Equilibrium of Multistage Phytoextractions
  Industrial & Engineering Chemistry Research 55 (2016) 1808–1812, (doi.org/10.1021/acs.iecr.5b04506)
   
• N. Wolters, G. Schembecker, J. Merz
  Erinacine C: A Novel Approach to Produce the Secondary Metabolite by Submerged Cultivation of Hericium erinaceus
  Fungal Biology, 119 (2015) 1334–1344, (doi.org/10.1016/j.funbio.2015.10.005)
   
• C. Schwienheer, A. Prinz, T. Zeiner, J. Merz
  Separation of active laccases from Pleurotus sapidus culturesupernatant using aqueous two-phase systems in centrifugal partition chromatography
  Journal of Chromatography, B 1002 (2015) 1–7, (doi.org/10.1016/j.jchromb.2015.07.050)
   
• B. Dreisewerd, J. Merz, G. Schembecker
  Determining the Solute-Solid Interactions in Phytoextraction
  Chemical Engineering Science, 134 (2015) 287-296, (doi.org/10.1016/j.ces.2015.04.025)
   
• C. Schwienheer, J. Merz, G. Schembecker
  Investigation, comparison and design of chambers used in Centrifugal Partition Chromatography on basis of flow pattern and separation experiments
  Journal of Chromatography A, 1390 (2015) 39-49, (doi.org/10.1016/j.chroma.2015.01.085)
   
• J. Krause, T. Oeldorf, G. Schembecker, J. Merz
  Enzymatic hydrolysis in an aqueous organic two-phase system using Centrifugal Partition Chromatography
  Journal of Chromatography A, 1391 (2015) 72-79, (doi.org/10.1016/j.chroma.2015.02.071)
   
• A. Hofmann,G. Schembecker, and J. Merz,
  Reply on " Comments on Role of bubble size for the performance of continuous foam fractionation in stripping mode"
  Colloids and Surfaces A: Physicochemical and Engineering Aspects, 474 (2015) 105–110, (doi.org/10.1016/j.colsurfa.2015.02.040)
   
• A. Hofmann, G. Schembecker, J. Merz
  Role of bubble size for the performance of continuous foam fractionation in stripping mode
  Colloids and Surfaces A: Physicochemical and Engineering Aspects, 473 (2015) 85-94, (doi.org/10.1016/j.colsurfa.2014.12.042)
   
• C. Schwienheer, J. Merz, and G. Schembecker
  Selection and use of poly ethylene glycol and phosphate based aqueous two-phase systems for the separation of proteins by Centrifugal Partition Chromatography
  Journal of Liquid Chromatography & Related Technologies, 38 (2014) 929-941, (doi.org/10.1080/10826076.2014.951765)
   
• F. A. van Winssen, J. Merz, L.-M. Czerwonka, G. Schembecker
  Application of the Tunable Aqueous Polymer-Phase Impregnated Resins-Technology for Protein Purification
  Separation and Purification Technology, 136 (2014) 123-129, (doi.org/10.1016/j.seppur.2014.08.030)
   
• J. Arens, D. Bergs, M. Mewes, J. Merz, G. Schembecker, and F. Schulz
  Heterologous fermentation of a diterpene from Alternaria brassisicola
  Mycology, 5 (2014) 207-219, (doi.org/10.1080%2F21501203.2014.917735)
   
• K. Stückenschneider, J. Merz, and G. Schembecker
  Molecular interaction of amino acids with acidic zeolite BEA: The effect of water
  Journal of Physical Chemistry C, 118 (2014) 5810-5819, (doi.org/10.1021/jp411734j)
   
• F.A. van Winssen, J. Merz, and G. Schembecker
  Tunable Aqueous Polymer-Phase Impregnated Resins-Technology – a novel approach to Aqueous Two-Phase Extraction
  Journal of Chromatography A, 1329 (2014) 38-44, (doi.org/10.1016/j.chroma.2014.01.001)
   
• K. Stückenschneider, J. Merz, and G. Schembecker
  Molecular interactions of alcohols with zeolite BEA and MOR frameworks
  Journal of Molecular Modeling, 19 (2013) 5611-562, (doi.org/10.1007/s00894-013-2048-9)
   
• K. Stückenschneider, J. Merz, F. Hanke, P. Rozyczko, V. Milman, and G. Schembecker
  Amino-Acid Adsorption in MFI-Type Zeolites Enabled by the pH-Dependent Ability to Displace Water
  The Journal of Physical Chemistry C, 117 (2013) 18927-18935, (doi.org/10.1021/jp4048709)
   
• D. Bergs, J. Merz, A. Delp, M. Joehnck, G. Martin, and G. Schembecker
  A Standard Procedure for the Selection of Solvents for Natural Plant Extraction in the Early Stages of Process Development
  Chemical Engineering & Technology, 36 (2013) 1739-174, (doi.org/10.1002/ceat.201300276)
   
• D. Bergs, J. Merz, A. Delp, M. Joehnck, G. Martin, and G. Schembecker
  Preparative purification of rebaudioside A from aqueous extracts using chromatography: A process idea
  Journal of Consumer Protection and Food Safety, 7 (2012) 295-303, (Article)
   
• D. Bergs, J. Merz, A. Delp, M. Joehnck, G. Martin, and G. Schembecker
  Preparative separation of rebaudioside A from stevia leaves using inverted chromatographic process design - An overview
  In: Geuns, Jan M.C. (Ed.), Stevia: 6 months beyond authorisation. Euprint, Heverlee, (2012) 105-112, ISBN: 978-90-742-53208
   
• J. Merz, B. Burghoff, H. Zorn, and G. Schembecker
  Continuous foam fractionation: Performance as a function of operating variables
  Separation and Purification Technology, 82 (2011) 10–18, (doi.org/10.1016/j.seppur.2011.07.023)
   
• J. Merz, H. Zorn, B. Burghoff, and G. Schembecker
  Purification of a fungal cutinase by adsorptive bubble separation: A statistical approach
  Colloids and Surfaces A: Physicochemical and Engineering Aspects 382 (2011) 81–87, (doi.org/10.1016/j.colsurfa.2010.12.007)
   
• J. Merz, G. Schembecker, S. Riemer, M. Nimtz, and H. Zorn
  Purification and identification of a novel cutinase from Coprinopsis cinerea by adsorptive bubble separation
  Separation and Purification Technology, 69 (2009) 57-62, (doi.org/10.1016/j.seppur.2009.06.021)

Oral presentations

• J. Krause, G. Schembecker and J. Merz
  Centrifugal partition chromatograph: A continuous multiphase reactor
  The 9th International Countercurrent Chromatography Conference, Chicago, USA (2016)
   
• J. Krause, G. Schembecker and J. Merz
  Centrifugal Partition Chromatography: A new reactor concept for enzyme catalysis
  3rd European Congress of Applied Biotechnology, Nice, France (2015)
   
• J. Krause, G. Schembecker and J.Merz
  Centrifugal Partition Chromatography: A new reactor concept for enzyme catalysis
  18th International conference in Biopartitioning and purification, Vienna, Austria (2015)
   
• J. Merz, F. A. van Winssen, and G. Schembecker
  Tuneable aqueous polymer phase impregnated resins in packed bed operation
  Jahrestreffen der Fachgruppen Extraktion und Mischvorgänge, Heidelberg, Deutschland (2015)
   
• F. A. van Winssen, J. Merz, and G. Schembecker
  Tunable Aqueous Polymer Phase Impregnated Resins: A New Approach for Protein Recovery
  AIChE Annual Meeting, San Francisco, USA (2013)
   
• J. Merz and G. Schembecker
  Foam fractionation a technique to separate enzymes from complex media
  Technologieseminar: Neue Ansätze für industrielle Trenntechniken in der Lebensmittel- und Biotechnologie, München, Deutschland (2013)
   
• J. Merz,, F. van Winssen, and G. Schembecker
  Investigation of Protein Partitioning in  Tunable Aqueous Polymer
  17th International conference in Biopartitioning and purification, Newport, USA (2013)
   
• J. Merz, C. Schwienheer, and G. Schembecker
  Selection and use of aqueous two phase systems in centrifugal partition chromatography
  9th International PhD Seminar on Chromatographic Separation Science, Weggis, Switzerland (2013)
   
• J. Merz, E. van de Sandt, G. Meesters, A. Schaap, and G. Schembecker
  Foam fractionation: A technique for process intensification
  9th conference on Foams and foam-related systems (fluid interfaces, thin films, surfactants, concentrated emulsions) EUFOAM, Lissabon, Portugal (2012)
   
• S. Adelmann, J. Merz, C. Schwienheer, and G. Schembecker
  Investigation of hydrodynamics in CPC chambers using image processing and computational fluid dynamics
  7th International Conference on Countercurrent Chromatography, Hangzhou, China (2012)
   
• J. Merz, E. Van de Sandt, G. Meesters, A. Schaap, and G. Schembecker
  Intensified downstream processing of PLA2 using foam fractionation
  16th International Conference on Biopartitioning and Purification (BPP), Puerto Vallarta, Mexico (2011)
   
• J. Merz, B. Burghoff, and G. Schembecker
  Continuous foam fractionation: Performance as a function of operating variables
  Vortrags- und Diskussionstagung: Bioverfahrenstechnik an Grenzflächen, Potsdam (2011)
   
• J. Merz, H. Zorn, B. Burghoff, and G. Schembecker
  Purification of a Fungal Cutinase by Adsorptive Bubble Separation: A statistical approach
  8th conference on Foams and foam-related systems (fluid interfaces, thin films, surfactants, concentrated emulsions) EUFOAM, Borovets, Bulgaria (2010)
   
• J. Merz, G. Schembecker, and H. Zorn
  Isolierung und Anreicherung von Pilzenzymen mittels fraktionierter Zerschäumung
  Vortrags- und Diskussionstagung "Biokatalyse: Neue Verfahren, neue Produkte", Bad Schandau (2009)
   
• I. Kaplanow, G. Schembecker, J. Merz
  Tunable Aqueous Polymer Phase Impregnated Resins: Contact angle as prediction parameter for impregnation
  31st Conference of European Colloid and Interface Society, Madrid, Spain (2017)
   
•  J. Krause, G. Schembecker, J. Merz
  Biocatalyst immobilization by centrifugal forces to enable continuous conversion and in situ product removal
  Himmelfahrtstagung: New Frontiers for Biotech-Processes, Koblenz, Germany (2016)
   
• I. Kaplanow, G. Schembecker, J. Merz
  Tunable Aqueous Polymer Phase Impregnated Resins Technology – Investigation of impregnation stability
  Himmelfahrtstagung:Scale-up and scale-down of bioprocesses, Hamburg, Germany (2015)
   
• N. Wolters, G. Schembecker, J. Merz
  Production of High Value Food Products by Fermentation of Biogenic Waste Streams
  Himmelfahrtstagung: Scale-up and scale-down of bioprocesses, Hamburg, Germany (2015)
   
• C. Schwienheer, J. Merz, G. Schembecker
  Aqueous two-phase systems for the gentle separation of bio-active compounds using centrifugal partition chromatography
  8th International Conference on Countercurrent Chromatography, London, UK (2014)
   
• J. Merz, B. Burghoff, H. Zorn, and G. Schembecker
  Determination of impact factors for continuous foam fractionation of the fungal enzyme cutinase
  8 th European Symposium on Biochemical Engineering Science, Bologna, Italy (2010)
   
• J. Merz, B. Burghoff, H. Zorn, and G. Schembecker
  A Statistical Approach for the Purification of a Fungal Cutinase by Foam Fractionation
  GVC / Dechema Vortrags- und Diskussionstagung: Bioprozessorientiertes Anlagendesign, Nürnberg (2010)