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Fakultät Bio- und Chemieingenieurwesen
Alumni

Felix Buthmann

Curriculum Vitae

Born February 16th, 1995 Bocholt (Germany)
2005 -2013 Bischöfliches St.-Josef-Gymnasium, Bocholt (Germany)
2013 - 2018 B.Sc. Biochemical Engineering Studies, TU Dortmund University
Bachelor Thesis: "Expression Systems for Polyketide Production in Escherichia coli"
2018 - 2019 M.Sc. Biochemical Engineering Studies, TU Dortmund University
Master Thesis: "3D Investigation of Diffusion Related Mass Transfer in liquid/liquid Flows Using X-ray Micro-computertomography"
Since 2020 PhD at the Laboratory of Plant and Process Design, TU Dortmund University
Field of Research: Centrifugal Partition Chromatography

Field of Research

In contrast to most Liquid Chromatography (LC) techniques, the Centrifugal Partition Chromatography (CPC) is based on differing solubilities of a target compound within the two phases of an immiscible liquid system.

In this work an experimentally verified model considering hydrodynamics and thermodynamics will be developed

Publications

Paper

  • Buthmann, Laby, Hamza, Koop, Schembecker
    Spatially and Temporally Resolved Analysis of Bleeding in a Centrifugal Partition Chromatograph
    Separations (2024), 11(2), 56  doi.org/10.3390/separations11020056
     
  • Buthmann, Hohlmann, Volpert, Neuwald, Hamza, Schembecker
    Counteracting Bleeding in Centrifugal Partition Chromatography: Redosing of the Stationary Phase
    Separations (2024), 11(4), 98 doi.org/10.3390/separations11040098
     
  • Buthmann, Hohlmann, Neuwald, Schembecker
    Optimizing Chromatographic Separation with Redosing: Effects on Separation Efficiency of a Model System in Centrifugal Partition Chromatography
    Separations (2024), 11(4), 111 doi.org/10.3390/separations11040111
  • Buthmann, Volpert, Koop, Schembecker
    Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography
    Separations (2024) doi.org/10.3390/separations11010016

  • Buthmann, Pley, Koop, Schembecker
    Automated Image Analysis for Retention Determination in Centrifugal Partition Chromatography
    Separations (2022) doi.org/10.3390/separations9110358

Oral presentations

  • Buthmann
    Centrifugal Partition Chromatography - Towards long-term Operation
    FAS Extraktion (2024), Dresden

  • Buthmann
    Centrifugal Partition Chromatography - Separation Performance Optimization during long-term Operation
    ECCE/ECAB (2023), Berlin

  • Buthmann
    Centrifgual Partition Chromatography - Optimization and Experimental Validation of long-term Operability
    Himmelfahrtstagung on Bioprocess Engineering (2022), Mainz
     
  • Buthmann
    Centrifugal Partition Chromatography - Optimization of long-term Operability and Implementation of Additive Manufacturing Approaches
    SoCSS (2022), Karlsruhe
     
  • Buthmann
    Towards long-term Operability - Towards long-term Operability: Redosing of Stationary Phase in Centrifugal Partition Chromatography
    Counter Current Conference (2022), virtual
     
  • Buthmann
    Centrifugal Partition Chromatography - Automatized Evaluation and Control of Stationary Phase Retention
    ECCE/ECAB (2021), virtual

Poster presentations

  • Buthmann, Laby, Schulte, Karan, Koop, Schembecker
    Centrifugal Partition Chromatography - Additive Manufacturing of a Rotor for Centrifugal Partition Chromatography
    FAS Extraktion (2023), Frankfurt

  • Buthmann, Neuwald, Schembecker
    Centrifugal Partition Chromatography - Separation Performance Optimization during long-term Operation
    Himmelfahrtstagung on Bioprocess Engineering (2023), Weimar

  • Buthmann, Laby, Schulte, Schembecker, Koop
    Design, Additive Manufacturing and Performance Benchmarking of a Rotor for Centrifugal Partition Chromatography
    (Bio)Process Engineering/ProcessNet (2022), Aachen