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Fakultät Bio- und Chemieingenieurwesen
Alumni

Fabian Görzgen

Profile picture: Fabian Görtzgen

Curriculum Vitae

Born Oktober 3rd, 1989 in Bochum (Germany)
2000-2009 Graf - Engelbert - Gymnasium, Bochum (Germany)
2009-2013 B.Sc. Chemical Engineering Studies, TU Dortmund University
Bachelor thesis: Laminar Operated Rotary Atomization in Spray Drying - Influence of Swirl Gas Flow on the Particle
2013-2017 M.Sc. Chemical Engineering Studies, TU Dortmund University
Master thesis: Investigation of the Kinetics in the TAPPIR®-Technology in Comparison to the Aqueous Two Phase Extraction
2017-2021 PhD at the Laboratory of Plant and Process Design, TU Dortmund
Field of Research: Application of the Novel Tunable Aqueous Polymer Phase Impregnated Resins (TAPPIR®)-Technology for Continuous Flow-Through Separation of Biomolecules

Field of Research

A key challenge impeding the transition of biocatalytic routes to full-scale production is the lack of cost-efficient purification of enzymes. The Tunable Aqueous Polymer Phase Impregnated Resins (TAPPIR®)-Technology is a novel approach for the purification of biomolecules, where one Aqueous Two Phase Extraction (ATPE) phase is immobilized in porous resins.

In this work within the NESEP project, the TAPPIR®-Technology will be incorporated in a column, transforming the current batch operated separation to a continuous flow-through separation. Thus the limitations of ATPE for industrial applications can be overcome and an efficient and environmentally benign purification technology for the downstream processing of enzymes will be provided.

Publications

Paper

  • Kaplanow, I., Goerzgen, F., Merz, J., Schembecker, G.
    Mass Transfer of Proteins in Aqueous Two-Phase Systems
    Scientific Reports 9(1) ( 2019) 3692, Article