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Fakultät Bio- und Chemieingenieurwesen
Mitglieder des Lehrstuhls auf einem Hochofen © Kerstin Wohlgemuth​/​TU Dortmund

Mareike Schreiber-Choo

Alumni

Profile picture: MAreike Schreiber-Choo

 

 

Curriculum Vitae

Born April 30th, 1994 in Kassel (Germany)
2010–2013 Georg-Christoph-Lichtenberg-Schule, Kassel (Germany)
2013–2017 B.Sc. Chemical Engineering Studies, TU Dortmund University
Bachelor thesis: Experimental and Theoretical Investigation of the Predictability of Solvent Flux Through Organic Solvent Nanofiltration Membranes
2017–2018 M.Sc. Chemical Engineering Studies, TU Dortmund University
Master thesis: Towards Characterization of a Continuous Oscillatory Baffled Crystallizer Using Small Volume Flow Rates
2019-2022 PhD at the Laboratory of Plant and Process Design, TU Dortmund University

Field of Research

For biotechnological products, a great amount of costs results from purification steps during downstream processing. In the present work, the main objective is to develop a platform that autonomously synthesizes and executes a downstream process based on heuristics, screening tests and statistical experiments. Thereby, the focus lies on steroid purification from a fermentation broth.

For this purpose, a robotic platform (Zinsser Analytic) is utilized which executes several unit operations in a miniaturized dimension and in an automated manner. Thus, material consumption, manual effort and variances of experimental results are minimized. Key performance indicators are applied to identify an economically optimized process with regard to costs, yield and purity.

As a result, suitable purification steps as well as optimal process conditions can be determined with the aid of the robotic platform.

Publications

Paper

  • M. Schreiber, G. Schembecker
    Development of an Automated Adsorbent Selection Strategy for Liquid–Phase Adsorption
    Chemical Engineering and Technology 45 (2022), No. 6, 1124-1132, doi.org/10.1002/ceat.202200152
     
  • M. Schreiber, M. Brunert, G. Schembecker
    Extraction on a Robotic Platform - Autonomous Solvent Selection under Economic Evaluation Criteria
    Chemical Engineering and Technology 44 (2021), No. 9, 1578-1584, doi.org/10.1002/ceat.202100171

Poster presentation

  • M. Schreiber, G. Schembecker
    Towards autonomous selection of adsorbents on a robotic platform utilizing economic evaluation indicators
    13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology, Virtual Meeting (2021)
     
  • M. Schreiber, L. Orth, G. Schembecker
    Towards Industry 4.0 - Autonomous Design of an Adsorption - Desorption Process on a Robotic Platform
    Jahrestreffen der ProcessNet-Fachgruppe Prozess-, Apparate- und Anlagentechnik, Virtual Meeting (2021)
  • M. Schreiber, G. Schembecker
    Approach for an Automated Synthesis of Downstream Processes Using a Robotic Platform
    Himmelfahrtstagung 2019, Hamburg, GER (2019)

Oral presentation

  • M. Schreiber, G. Schembecker
    Towards Automated Downstream Process Design - Development of a Tool for Autonomous Adsorbent Selection
    Jahrestreffen der ProcessNet Fachgruppe Adsorption, Frankfurt, GER (2021)
  • M. Schreiber, M. Brunert, G. Schembecker
    Advances in Industry 4.0 – Development of a Smart Robotic Platform for Autonomous Synthesis of Downstream Processes
    Pre-recorded +, Virtual AIChE Annual Meeting, 2020
  • M. Schreiber, G. Schembecker
    Liquid-Liquid Extraction on a Robotic Platform – A Step towards Automated Downstream Process Design
    Jahrestreffen der ProcessNet-Fachgruppen Fluidverfahrenstechnik, Adsorption und Extraktion
    Berchtesgaden, GER (2020)
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