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Laboratory of Plant and Process Design Emil-Figge-Str. 70 Geschossbau 2 44227 Dortmund Deutschland
Room G2-R3.14
B.Sc. Chemical Engineering Studies, TU Dortmund University
Bachelor thesis: Development of a Method for determining the Primary Nucleation Threshold in a Continous Oscillatory Baffled Crystallizer
M.Sc. Chemical Engineering Studies, TU Dortmund University
Master thesis: Development of an inter gassing crystallization and solid-liquid separation for an integrated catalyst recycling process
PhD at the Laboratory of Plant and Process Design, TU Dortmund University
Field of Research: Continuous crystallization, Continuous solid-liquid separation
For the paradigm shift from batch to continuous operation in pharmaceutical industry, innovative process solutions are required to extend unit operations that have historically been batch operations, such as crystallization. Different concepts for continuous crystallization are present to improve the product qualities such as crystal size, shape, and purity. However, crystallization needs additional downstream processes as filtration, washing and drying to obtain the final product.
These continuous isolation techniques are relatively rare in the pharmaceutical industry and specialty chemical industry, because of relatively low production capacities. The lack of commercial laboratory and manufacturing continuous filtration units leads to a significant gap in the development of full continuous manufacturing processes. Thus, a continuous small-scale solid/liquid filtration device will be developed and characterized. Subsequently, the device will be connected to different continuous crystallizers to enable a full continuous process.Funding: This research work is funded by the state of North-Rhine Westphalia (NRW) and the European Regional Development Fund (EFRE), Project “NRW Patent Validation Program” (Grant EFRE-0400357).
