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Anne Cathrine Kufner

Anne Cathrine Kufner Photo of Anne Cathrine Kufner

(+49)231 755-2014

(+49)231 755-2341

Consultation hours
via Email


Laboratory of Plant and Process Design
Emil-Figge-Str. 70
Geschossbau 2
44227 Dortmund

Room G2-R3.14


Born August 26th, 1995 in Mönchengladbach (Germany)
2006 - 2014 Gymnasium St. Wolfhelm, Schwalmtal (Germany)
2014 - 2018

B.Sc. Chemical Engineering Studies, TU Dortmund University

Bachelor thesis: Inline-Analysis of Suspensions in FEP-Capillaries with Ultrasonics

2018 - 2020

M.Sc. Chemical Engineering Studies, TU Dortmund University

Master thesis: Operating Behavior of a Slug Flow Crystallizer with Focus on Enhanced Product Quality Control

Since 2020 PhD at the Laboratory of Plant and Process Design, TU Dortmund University
Field of Research: Continuous crystallization

Field of Research

In the context of maintaining consistent product quality such as a specific and narrow crystal size distribution (CSD), purity or morphology, the use of continuous crystallizers offers several advantages compared to batch crystallizers for the production of e.g. pharmaceutical products.

One of these continuous crystallizers is the slug flow crystallizer (SFC), characterized by the liquid segmentation through a gaseous phase and the maintenance of a narrow residence time distribution. This feature and the internal circulation within the liquid slugs without external devices ensure the achievement of increased product quality within very short process times.

The project focuses on the crystallization process in the apparatus, improvement in process efficiency and assurance of in-spec product crystals. Basic approach is the separation of nucleation and growth zone in order to enhance the control of crystallization phenomena.




  • Anne Cathrine Kufner, Adrian Krummnow, Andreas Danzer, Kerstin Wohlgemuth
    Strategy for fast decision on material system suitability for continuous crystallization inside a Slug Flow Crystallizer
    Micromachines (2022) https://www.mdpi.com/2072-666X/13/10/1795

  • Claas Steenweg, Anne Cathrine Kufner, Jonas Habicht, Kerstin Wohlgemuth
    Towards Continuous Primary Manufacturing Processes - Particle Design through Combined Crystallization and Particle Isolation
    Processes (2021), 9, 2187

  • Maren Termühlen, Matthias Markus Etmanski, Ines Kryschewski, Anne Cathrine Kufner, Gerhard Schembecker, Kerstin Wohlgemuth
    Continuous Slug Flow Crystallization: Impact of Design and Operating Parameters on Product Quality
    Chemical Engineering Research and Design 170 (2021) 290–303

Oral presentations

  • A.C. Kufner, C. Steenweg, J. Habicht, K. Wohlgemuth
    Towards a continuous crystal process chain of high quality products
    CKB Final Symposium, Düsseldorf (2021)

  • A.C. Kufner, C. Steenweg, J. Habicht, K. Wohlgemuth
    Process integration of continuous Slug Flow Crystallization and product isolation using Modular Continuous Vacuum Screw Filter
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Dortmund (2022)

Poster presentations

  • A.C. Kufner, C. Steenweg, J. Habicht, K. Wohlgemuth
    Particle Design Through Combined Continuous Slug Flow Crystallization and Particle Isolation
    BIWIC, Espoo, Finland (2022)

  • A.C. Kufner, F. Gjoni, N. Westkämper, K. Wohlgemuth
    Towards long-term operability of a continuous Slug Flow Crystallizer – Nucleation, suspension behavior, and blockage avoidance
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Dortmund (2022)

  • A.C. Kufner, M. Termühlen, K. Wohlgemuth
    Towards increased product quality inside a Slug Flow Crystallizer (SFC)
    21st ISIC - International Symposium on Industrial Crystallization, Virtual Meeting (2021)

  • A.C. Kufner, M. Termühlen, G. Schembecker, K. Wohlgemuth
    Impact of operating parameters on continuous Slug Flow Crystallization
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Virtual Meeting (2021)