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Stephan Adelmann

Stephan Adelmann Photo of Stephan Adelmann

(+49)231 755-2339

(+49)231 755-2341


Laboratory of Plant and Process Design
Emil-Figge-Str. 70
Geschossbau 2
44227 Dortmund

Room G2-R3.20

Staff Information

Short Presentation

Stephan Adelmann studied mechanical engineering with the majors process design and biomedical engineering at the Leibniz University of Hanover. He completed his degree in 2008 with his thesis on "Calculation of the energy conversion in a screw type motor based on a multiphase screwpump". Since October 2008 he is employed at the laboratory of plant and process design and his research as a Ph.D student focuses on centrifugal partition chromatography (CPC). From November 2006 to April 2007 he completed an internship in Mobile, Alabama, USA for Degussa (today Evonik) in the field of integrated process development.


Centrifugal Partition Chromatography is mainly used for preparative scale purification of natural products. Separation is based on the different solubilities of the compounds in the two phases of an immiscible liquid mixture. Therefore one phase flows through the other phase which is kept stationary by the forces of centrifugation. Compared to other chromatographic separation processes a direct scale-up of CPC is possible and the absence of a solid phase avoids irreversible adsorption.
The aim of this work is the analysis and modeling of the hydrodynamics in a so called static centrifugal partition chromatograph. Thereto the dispersion and coalescence properties of various two phase systems are investigated by stroboscopic exposure of the two phase flow to describe the influence on the separation efficiency.





  • S. Adelmann, G. Schembecker
    Influence of physical properties and operating parameters on hydrodynamics in Centrifugal Partition Chromatography
    In press (doi:10.1016/j.chroma.2011.01.064)
  • S. Adelmann, C. Schwienheer, G. Schembecker
    Multiphase flow modeling in Centrifugal Partition Chromatography
    In press (doi:10.1016/j.chroma.2011.01.063)

Oral presentations


  • S. Adelmann, J. Merz, C. Schwienheer, and G. Schembecker
    Investigation of hydrodynamics in CPC chambers using image processing and computational fluid dynamics
    7th International Conference on Countercurrent Chromatography, Hangzhou, China (2012)
  • S. Adelmann, C. Schwienheer, G. Schembecker
    Hydrodynamic analysis in Centrifugal Partition Chromatography using experimental visualization and multiphase flow modeling
    7. Doktorandenseminar "Präparative Chromatographie", Wernigerode, Deutschland (2011)
  • S. Adelmann, C. Schwienheer, G. Schembecker
    Multiphase flow modelling in Centrifugal Partition Chromatography
    VIth International Conference on CounterCurrent Chromatography (CCC 2010), Lyon, Frankreich (2010)
  • M. Stadler, J. Bitzer, B. Köpcke, S. Adelmann, G. Schembecker, T. Shen, H. Zorn
    Fermentation, Downstream Processing and Isolation of Biologically Active Terpenoids From Cultures of Cyathus and Hericium spp. (Basidiomycota)
    Materials Valley Workshop "Rote und Weiße Biotechnologie: Herstellung von Substanzen mittels Fermentationsverfahren, deren Aufarbeitung und Reinigung", Hanau, Deutschland (2010)
  • S. Adelmann, G. Schembecker
    Hydrodynamik in einem Zentrifugalchromatographen (Hydrodynamics in Centrifugal Partition Chromatography)
    6. Doktorandenseminar "Präparative Chromatographie", 2010


Poster presentations

  • S. Adelmann, G. Schembecker
    Influence of physical properties and operating parameters on hydrodynamics and separation efficiency in CPC
    13th Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA 2010), Stockholm, Schweden (2010)
  • S. Adelmann, G. Schembecker
    Flow Visualization in Centrifugal Partition Chromatography
    GVC / Dechema Vortrags- und Diskussionstagung: Bioprozessorientiertes Anlagendesign, Nürnberg (2010)
  • S. Adelmann, T. Winkelnkemper, G. Schembecker
    Selection of Solvent Systems in Centrifugal Partition Chromatography
    ACHEMA 2009, Frankfurt am Main, Deutschland (2009)