Telephone (+49)231 755-2339
Fax (+49)231 755-2341
Laboratory of Plant and Process Design Emil-Figge-Str. 70 Geschossbau 2 44227 Dortmund Germany
Room G2-R3.20
Pascal Scherpian graduated from Dortmund University in 2004. He finished his studies in chemical engineering with a thesis on conceptual design of integrated reaction and separation processes. Employed at the laboratory for plant and process design from January 2005 his research focuses on the synthesis of chromatographic separation processes.
As standard unit operation preparative chromatography is a popular technique when it comes to purification of fine chemicals and biotechnological products. Seeking for a fast implementation of chromatographic processes very often classical batch chromatography is applied. With rising production scales and separation cost becoming more important a simulated moving bed (SMB) unit might be considered, instead. However, smaller companies are often reluctant to invest in such complex equipment. In this case advanced batch process concepts like closed-loop (CLRC) and steady-state (SSRC) recycling chromatography are promising alternatives, because they consist of flexible and inexpensive equipment and they can lead to higher yield and productivity. Optimisation and design of recycling chromatography processes form the basis to generate a knowledge base assisting the choice of process concept during process development.
