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Jan-Bernd Große Daldrup

Jan-Bernd Große Daldrup

(+49)231 755-2339

(+49)231 755-2341


Laboratory of Plant and Process Design
Emil-Figge-Str. 70
Geschossbau 2
44227 Dortmund

Room G2-R3.20

Staff Information

Short Presentation

Jan-Bernd Grosse Daldrup studied Chemical Engineering at the University of Dortmund and finished his studies with a diploma thesis dealing with the preparation and characterization of heterogeneous catalyst supports for the use in processes with dynamic pressure manipulation ("Erstellung und Charakterisierung heterogener Katalysatorträger für die Anwendung in Prozessen mit instationärer Druckführung ") at the Laboratory of Chemical Reaction Engineering in August 2006. Since October 2006, he is working on his PhD at the Laboratory of Plant and Process Design. In his research he focuses on the crystallization of multi solute solutions and upscale of batch crystallizers.



The aim is to characterize the solubility and the crystallization behaviour of multi solute solution such as fermentation broths and the upscale of batch crystallizers. In multi solute solutions the solubility of the main solute depends on several parameters such as e.g. the temperature and concentration of co-solutes. As these parameters define the thermodynamics of the system the co-solute concentration also influences the kinetics of the crystallization process, such as nucleation and growth kinetics. These parameters are measured in an aqueous amino acid solution as amino acids are mostly produced by fermentation. The gathered information should be used to model the crystallization process and optimize it towards a narrow crystal size distribution as this is needed for the following downstream process, such as e.g. filtering or washing




  • Große Daldrup, Jan-Bernd; Held, Christoph; Ruether, Feelly; Sadowski, Gabriele; Schembecker, Gerhard
    Measurement and modeling solubility of aqueous multi solute amino acid solutions
    Industrial & Engineering Chemistry Research 49, (2010), S.1395-1401
  • J.-B. Große Daldrup, G. Schaldach, P. Walzel
    Herstellung von Hohlpartikeln durch Eintropfgranulation
    Chemie Ingenieur Technik 81 (6), (2009), S. 833-838.


Oral Presentation

  • J.-B. Große Daldrup, D. Focke, F. Rüther, G. Schembecker
    Kristallisation von Aminosäuren aus Fermentationslösungen
    Jahrestreffen des Fachausschusses Kristallisation, Magdeburg, Deutschland  (2010)
  • C. Held, F. Rüther, G. Sadowski, J.B. Grosse-Daldrup, G. Schembecker
    Thermodynamische Eigenschaften von wässrigen Aminosäurelösungen
    ProcessNet Jahrestagung 2009, Mannheim, Deutschland  (2009)
  • F. Tumakaka, G. Sadowski, J.-B. Große Daldrup, G. Schembecker
    Solubility of biological and industrial important organic compounds
    7th European Symposium on Biochemical Engineering Science (ESBES), Faro, Portugal (2008)
  • J.-B. Große Daldrup, G. Schembecker, F. Tumakaka, G. Sadowski
    Measurment and modeling solubility of two amino acids and of two enantiomers in aqueous solution
    2nd international Symposium on Biothermodynamics, Frankfurt, Germany (2008)