Telephone (+49)231 755-2339
Fax (+49)231 755-2341
Laboratory of Plant and Process Design Emil-Figge-Str. 70 Geschossbau 2 44227 Dortmund Germany
Room G2-R3.20
Ivana Barackov studied at the Faculty of Food Technology at University J. J. Strossmayer in Osijek, Croatia, majors Process Engineering. She finished her studies in October 2008 with her diploma thesis "Synthesis of 4-Thiazolidines from different Thiosemicarbazides". Since November 2009, she is doing her research work at the Laboratory of Process and Plant Design on innovative downstream processes, with emphasis on the processes of foam fractionation.
Foam fractionation is a gentle and selective recovery step for enzymes. This separation step is based on the ability of water soluble, surface active substances to adsorb on gas-liquid interfaces, e.g. gas bubbles. The main application of this method is the concentration and isolation of dilute aqueous protein mixtures as occurring in fermentation processes.
The aim of research is therefore to find ways to deal with these peculiarities. The goal is to show on the molecular level how proteins, specifically cutinase, BSA and lysozyme, fold and how an enzyme acts at the gas-liquid interface. The influence of salts, pH and temperature on the protein structure would be also determined. Based on the results of this molecular study other protein molecules shall be evaluated for their potential separation by foam fractionation. Finally, a pattern for upscaling foam fractionation processes derived from the molecular study shall be developed.
GEFÖRDERT VOM:
Poster presentation
